Ginkgo Biloba Extract
1.Description

Ginkgo biloba extract (GBE) is a kind of yellow brown powder, extracted from Ginkgo biloba leaves. The main active constituents include terpene lactones and flavone glycosides. GBE is marketed in dietary supplement form with claims it can enhance cognitive function in people without known cognitive problems.
Cas No.: 90045-36-6
HS No.: 13021940.00It has been filed by the State Administration of drug administration, and the record number is ZTCB20160189SU.

2.Chemical Structure

R=OH Quercertin(bilobalide) derivative
R=H Kaempferol derivative
R=OCH3 Isorhamnetin derivative

R1=OH, R2=R3=H Ginkgolide A
R1=R2=OH, R3=H Ginkgolide B
R1=R2=R3=OH Ginkgolide C

3.Quality Specification

Items Chinese Pharmacopoeia 2015 Company Standard
Appearance Yellow-brown powder, a slight bitter taste
Loss on drying ≤5.0% ≤4.0%
Residue on ignition ≤0.8% ≤0.8%
Peak area ratio of flavoniod glycones Peak area ratio of quercetin and kaempferol should be in the range of 0.8-1.2; peak area ratio of isorhamnetion and quercetin should be not less than 0.15. Peak area ratio of quercetin and kaempferol should be in the range of 0.8-1.2; peak area ratio of isorhamnetion and quercetin should be not less than 0.15. Peak area ratio of quercetin and kaempferol should be in the range of 0.8-1.2; peak area ratio of isorhamnetion and quercetin should be not less than 0.15. Peak area ratio of quercetin and kaempferol should be in the range of 0.8-1.2; peak area ratio of isorhamnetion and quercetin should be not less than 0.15.
Ginkgolic acid ≤10mg/kg ≤10mg/kg
Flavone glycosides ≥24.0% ≥24.30%
Terpene lactones ≥6.0% ≥6.35%
Free quercetin / ≤10.0mg/g
Free kaempferol / ≤10.0mg/g
Free isorhamnetion / ≤4.0mg/g
Aerobe(cfu/g) ≤1000 ≤800
Mould & Yeast(cfu/g) ≤100 ≤50
E.coil(1g) Not detected Not detected

4. Function and Use

GBE has a number of health benefits, including enhancing cognitive function and providing support for better memory functions. It has been used for improving blood flow, for improving memory/concentration due to certain brain problems (e.g., Alzheimer's disease, dementia), and for relief of premenstrual syndrome (PMS), eye problems, and dizziness. It also provides powerful antioxidant properties.

5. Packaging and Storage

25kg/drum
25kg/drum
Sealed store in a cool, dry place away from direct sunlight
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